Friday, March 29, 2013

Razer begins shipping Edge units to those who pre-ordered this month

Razer begins shipping Edge units to those who preordered this month

Back when the Razer Edge pre-orders kicked off, on March 1st, the company wasn't quite clear as to when exactly the device would commence shipping to early adopters, only going as far as saying it would be later that very month. Well, the good news is today Razer took to its own Facebook page to announce that its new-era gaming PC is now on its way to folks who put in a pre-order "from the March batch." Meanwhile, Razer's hoping other gamers will also shell out the hefty amount of $999-plus for its novel piece of hardware, urging potential buyers on the social network to snag a unit (or two) before they go out of stock -- just don't expect to get a keyboard dock with your order, as the previously reported Q3 availability for this add-on remains intact. Above all, however, it's a great thing to see that what was once just a project, is now getting ready to arrive at consumers' doorsteps.

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Source: Razer (Facebook)

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/BmDpEEys0mU/

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Gay News Headlines - Gay Rights, Marriage, Relationships

GAYTWOGETHER disclaims any and all responsibility or liability for the accuracy, content, completeness, legality, reliability, operability, or availability of information or material displayed on this site and does not claim credit for any images or articles featured on this site, unless otherwise noted. Usually we try to give credit when and where we can. All visual content is copyright to it's respectful owners. Information on this site may contain errors or inaccuracies, the site's proprietors do not make warranty as to the correctness or reliability of the site's content. If you own rights to any of the images or articles, and do not wish them to appear on this site, please contact us via e-mail and they will be promptly removed. GAYTWOGETHER contains links to other Internet sites. These links are provided solely as a convenience to you and are not endorsements of any products or services in such sites, and no information in such site has been endorsed or approved by GAYTWOGETHER.

Source: http://gaytwogether.typepad.com/gaytwogether/2013/03/gay-news-headlines-gay-rights-marriage-relationships.html

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How Copywriting Creates Six-Figure Incomes | Ray Edwards

If you think ?copywriting? (writing words that persuade people to do or buy something) is only about creating ads, you?re missing the point. Copywriting is a skill has created more six-figure incomes than you might imagine. In some cases, seven-figure incomes.

Type writer

For instance, one of my best friends generates a healthy $150,000 per month from his home-based business, and at its core, that business is fueled by my friend?s copywriting skill.

If you truly want to start your own business, or create a second income stream, one of the first things I would recommend you learn is the basic skill of powerful copywriting.

Now, this is not some ?get rich quick? scheme?

This is a serious business skill than can provide you with a comfortable six-figure annual income for the rest of your life.

You can run your business from anywhere. You can dream up promotions and campaigns, write the copy, and put the plan into profit? all in the same day.

And yes, you could ?retire? from your present job, and use your copywriting skills to build your own marketing empire?- working wherever and whenever you want.

I have run my business from all over the USA, Canada, Mexico, the Caribbean, and the UK:

  • Working form home in the Northwest US (sometimes at my house, sometimes from my office 5 minutes away, and sometimes from Starbucks!)?
  • On the road in my motorhome (summer-before-last we put 8,000 miles on the coach, the last winter we spent in California)?
  • Traveling to Chicago, San Diego, Los Angeles, Seattle, Toronto and New York?
  • On vacation with family in Michigan, the Carolinas, Utah, and Montana?
  • And from England and Scotland?

My results are not typical?- you?ll have your own results. Want to join me in the ?not typical? club? Want to know how I managed to get these unusual results?

It comes down to one skill: copywriting. Now, ask yourself? if you learned how to master the art of ?persuasion in print?, how could that change your life?

  • Will you finally get your online business started?
  • Will you write copy freelance, and live a life free from offices, meetings, and memos?
  • Will you take your existing online business and multiply your profits using the power of copy?

Or will you keep struggling along like most ?Internet Marketers?? That road leads nowhere. You don?t need to learn the new ?shiny object of the week? system. You don?t need the latest greatest website.? You just need a skill that is valued, and that has the power to give you leverage. The skill I recommend starting with is the ability to write persuasive copy.

If you have decided that I am right about this, give life to that decision and do something about it. Pick up a book, take a copywriting course, or just sit down and write a piece of copy. Today. Maybe even right now.

A good place to start would be with my book on copywriting. An even better place to start would be with the live webinar training about copywriting I?m doing next Tuesday.

Question: How can you profitably apply the power of persuasive copy in your business?

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Gut-Microbe Swap Helps with Weight Loss

A bacterial transplant in mice has been shown to provide some of the benefits of gastric bypass surgery without putting the animals under the knife


gut microbe, gastric bypass Here the taxonomy of gut bacteria in mice that have received gastric bypass (red) is compared to that of mice kept at the same weight (blue) and of others that were not kept on a diet (green). Image: Science Translational Medicine/AAAS

Obese people considering gastric bypass surgery to help trim their fat might one day have another option: swallowing a new supply of gut bacteria. A study in mice suggests that weight loss after bypass surgery is caused not by the operation itself, but at least in part by a change in the amounts of various species of microbes in the gut.

A bypass operation separates off a small part of the stomach and connects that directly to the intestines. Recipients tend to feel less hungry, fill up more quickly and burn more calories at rest, and they often lose up to 75% of their excess fat. Counter-intuitively, this is thought to be caused by a change in metabolism, rather than by the reduced size of the stomach.

Gut microbes are thought to be part of this picture. People who have had bypasses are known to experience changes in the selection of microbes in their guts. Fat people have been shown to host a different selection of gut bacteria from people who are obese, and transferring the gut bacteria of fat mice into thin ones can cause the thin mice to pack on extra weight. But no one knew whether the microbes in bypass patients changed because they got thin, or if the patients got thin because the microbes changed.

Chop and change
To investigate, Lee Kaplan, director of the Obesity, Metabolism and Nutrition Institute at Massachusetts General Hospital in Boston, and his colleagues gave about a dozen obese mice bypass surgery. As expected, the mice lost about 29% of their body weight, and kept it off despite a high-fat diet. New conditions in their bodies ? such as a change in bile acids ? allowed a different set of gut bacteria to thrive.

The researchers then took faecal samples from the mice that had been operated on, and put bacteria from them into the guts of mice specially bred without any gut flora. These mice, which were not obese, lost 5% of their weight without any changes to their diet. The results are reported in Science Translational Medicine.

The effect is impressively large, says Randy Seeley, an obesity researcher at the University of Cincinnati in Ohio, particularly given that sterile mice almost always gain weight when given any kind of gut flora. The fact that the mice getting the second-hand bacteria did not lose as much weight as those that had surgery suggests that other factors are also at work; these could include hormonal changes.

The results are promising for obesity treatments, but there are still hurdles to overcome. ?You can?t just take a pill of the right bacteria and have them stick around,? says Seeley. If the gut?s environmental conditions don?t change, then the original microbes come back, he says. Kaplan says that the next steps are to isolate the four bacteria types that the study found to be at play and introduce them into obese mice or people. Antibiotic treatments might help the new bacteria to stick. ?I believe it?s possible,? says Kaplan.

This article is reproduced with permission from the magazine Nature. The article was first published on March 27, 2013.

Source: http://rss.sciam.com/click.phdo?i=fca6fa7a6f995e1106279c0f34dc1c43

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Thursday, March 28, 2013

Art 7 Entertainment: A To Z Of Well-Known Magicians


There are many well-known, skilled magicians that you might not know about because even though they're well known, they haven't reached magician cult status. Most people know about the magician David Copperfield, but there are many more magicians equally skilled. So, take a moment to learn about other wizards of magic and expand your knowledge about magicians.

Curtis Adams: A magician who appeared at the age of 16 in the Young Magicians Showcase featured on Fox Television. He was born on October 12, 1984 and was one of the youngest magicians to perform in Reno, Nevada casinos.

Criss Angel: The only three-time magician winner of the Merlin Award from the International Society of Magicians. Angel is a skilled magician who did stunts like lying on a bed of nails while a Hummer drove over him.

Ed Balducci: A street magician who died in 1988 at the age of 82. He is a magician known for his gimmick-free trick of visibly rising several inches from the ground with his back turned to his audience.

Derren Brown: A British magician who practiced traditional close-up magic in the 1990s. Brown's claim as a magician is his "mind-reading" act. Brown claims aliens abducted him.

Cardini: Richard "Cardini" Pitchford was a magician with almost 50 years of performing tricks and illusions. He's one of the world's most imitated magicians, but no one to date has ever been able to completely duplicate his tricks. He was a magician known for his sleight of hand. Items were forever appearing and disappearing from his hands. He died in 1973.

Tommy Cooper: A magician and comedian known who was a member of the Magic Circle until his death in 1984. He collapsed while doing a live magician act that became his last.

Paul Daniels: A currently retired British magician who in 1983 became the first magician to ever receive the prestigious Magician of the Year Award by the Hollywood Academy of Magical Arts.

S.W. Erndase: A magician and author whose real identity has never been figured out. Erndase is a magician who wrote a book in 1902 about card playing tricks.

Ching Ling Foo: The first Asian magician to achieve fame. He was a magician who did tricks like breathing fire and pulling a fifteen-foot pole from his mouth. He died in 1922.

Lennart Green: A magician known for his close-up card tricks. In 1991 this magician became the world champion of in close-up card magic.

Paul Harris: A magician known for pulling coins from mirrors. Many claim he is a magician with skills like a combination of Copperfield and Henning.

Scott Interrante: An American magician specializing in escape-artist tricks. He won awards from the International Brotherhood of Magicians.

Ricky Jay: A magician listed in the Guinness Book of Records as throwing a playing card 190 feet at 90 miles per hour.

Fred Kaps: A Dutch magician who died in 1980. He is a magician known for making a saltshaker create an endless supply of salt.

Juan Tamariz: A Spanish magician who in 1971 founded a school that has trained generations of Spanish magicians.

Dia Vernon: This Canadian magician was born in 1894 as David Frederick Wingfield Verner. This magician, who died in 1992, is known for fooling Houdini with one of his card tricks.

Paul Zenon: A British street magician who also performed in the bars and pubs in the U.K. This magician has written three books about magic, the most recent published in 2005.


Source: http://art7entertainment.blogspot.com/2013/03/a-to-z-of-well-known-magicians.html

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Outsourcing Telemarketing Services for Win Solution

For many small and medium sized businesses, outsourcing telemarketing services is an important and necessary step. ?If you don?t have the manpower or resources to handle telemarketing in house, outsourcing your telemarketing can free you and your employees to focus on the important, day to day operations of your business. ?Outsourcing telemarketing services turns over that job to those people who specialize in it. ?Outsourcing can also save your business some money. ?It?s a win/win situation, right?

Well, it is a good option for many businesses. ?However, don?t overlook the fact that outsourcing does require some maintenance on your part. ?Outsourcing telemarketing services is not just a matter of hiring a company and walking away. ?You will have to do some follow-up work along the way.

In order to hold up your end of the bargain as the outsourcer, these are some of the things that you must do:

  1. Prepare job information list.
    Provide the information that the telemarketing service needs to do its job. ?You will have to give them some basic information to get started with. ?Make sure that you give your name and contact number to the telemarketing service, even if you are just casually looking for information online. ?They are trying to develop new leads, just like you are.
  2. Tell them what you want.
    The telemarketing service cannot give you what you want from them if you do not make your needs explicitly clear. ?The importance of this point cannot be stressed enough. ?If you expect results from your telemarketing service, you must equip them to do their job by clearly outlining and defining what you expect from them. ?If you are looking for an increase in revenue, specifically state the number that you are looking for. ?If you want the telemarketing service to make a certain number of calls per day, say so. ?If you want a certain number of representatives to be assigned to your account, let them know. ?The most critical step in determining your outcome is clearly stating your goals and objectives.
  3. Learn where to get access to your results.
    Telemarketing services keep track of all sorts of statistics related to your campaign. ?They will prepare reports on things like total increase in revenue, number of calls made, the increase in sales by demographic, and sales by customer service representative. ?All the reports in the world don?t do you any good if you don?t know where or how to get them, though. ?Find out if the reports will be sent to you on a regular basis. Some companies give you access to their database so that you can check the reports whenever you wish. ?Whatever the system for relaying reports, you should know what you are signing up for.

When you outsource your telemarketing services, you can save a lot of time, stress and money. You just need to do a little bit of work at the outset and some periodic follow up. ?The clearer you are at the outset of your relationship, the better your results will be.

Let the expert team at Forlex Sales handle all of your outsourced telemarketing activities. Our team is highly trained to meet the needs of every business owner. In addition to telemarketing, we also offer application verification, lead generation, prospect research, rapid inquiry response, live real time transfers, market research, and everything else you need to grow your business.

Outsourcing Telemarketing Services
Forlex Sales was founded by a group of experts who specialize in marketing and information technology, so we understand how important it is to stay up to date with your information and your technology.

Contact us for?complimentary consultation?to make sure we are the best partner for your business.

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Source: http://www.forlexsales.com/general-information/outsourcing-telemarketing-services/

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Prostate cancer breakthrough: Q&A | Science | guardian.co.uk

Scientists have hailed the "single biggest leap forward" in their understanding of the genetic causes of prostate cancer, from a huge study involving more than 1,000 scientists.

The research has also brought significant advances in unravelling the genetics of breast and ovarian cancers. This is how the Guardian's science correspondent Ian Sample described the research:

The study, the largest ever to look for faulty DNA that drives the cancers, revealed scores of genetic markers that can identify people most likely to develop the diseases at some point in their lives.
Doctors said a simple ?5 spit-test based on the markers could provide patients with a personalised "risk profile" for the diseases and pave the way for individually tailored screening, with those most at risk having more regular health checks.
The findings have major implications for the treatment of prostate cancer. A test based on genetic markers for the disease could identify men whose lifetime risk was a staggering 50%, nearly five times the national average.
Ros Eeles, professor of cancer genetics at the Institute of Cancer Research in London, described the results as "the single biggest leap forward" in understanding the genetics of the disease.
A screening service could be offered within five years, and would transform medical treatment for the most common cancer among British men. More than 40,000 men a year are diagnosed with prostate cancer in Britain, and almost 11,000 die from the disease.

We have invited Prof Douglas Easton, director of the Cancer Research UK Genetic Epidemiology Group at the University of Cambridge, who worked on the studies, to answer your questions about their significance and the implications for future genetic tests for the diseases and potential treatments.

Here are a selection of your questions answered by Prof Easton:

JennM
My father was treated successfully for prostrate cancer - they caught it early and he only had one operation that I can recall - something about freezing the prostrate - It that possible? It was a while ago, and since there were no complications, it seemed a very benign cancer. I see now that it is dangerous, but perhaps it is important to catch it early.

My question is, with the new discovery, could there be vaccinations against this cancer (and other cancers) like the current vaccination against cervical cancer?

Prof Easton:
@JennM - so far there has been no evidence that prostate cancer is caused by a virus. The new discoveries should provide a lot of information about how prostate cancer develops, by studying the genes that are involved, and potentially what causes it. Unfortunately we still know very little about what actually causes prostate cancer.

James Sherry
Does this test relate to the promise of genetic therapy for the disease?

Prof Easton:
@James Sherry - the discoveries not relate directly to any type of therapy - they tell us about markers that increase the risk of disease. However, the next step is to understand how these markers increase risk and, in particular, which genes that affect. This information could be used to develop drugs (or, in some cases, there may already be drugs that target the genes on interest). There are already examples of this for other diseases. But it is likely to be a long process.

Rasputin9000
It is easy to imagine that if someone is told they have a whole lot of cancer-promoting genes, they might decide (in the future when such techniques are more perfected, say in 10 years) to use IVF instead of natural impregnation, and to kill off the fertilised eggs that turn out to contain the genes.

Is it likely, if people then succeeded in reducing the incidence of these cancer-promoting genes, that it would have a negative impact on the gene pool, as the same genes could also affect something else?

Prof Easton:
@Rasputin9000 - it is certainly possible that the genetic markers linked to cancer risk could also be linked to something else (indeed we already know examples of this, where for example they are linked to the risk of diabetes).

However I dont think there any question of utilising this type of information for preimplantation testing. That can be appropriate for certain "single gene" disorders with a high risk of a particular disease, but will is not (to my my mind at least) ever be a realistic possibility for these common disease with many many genetic variants, even if it was desirable.

SarahCadge
I'm in my 30's and am screened annually due to an increased risk of breast cancer; that risk is due to familial incidence - no one affected has tested positive for BRCA1, BRCA2 or TP53. What is this development likely to mean for me, if anything?

Prof Easton:
@SarahCadge - at the moment annual screening from a young age is recommended (by NICE) for women with a strong family history of the disease. The new markers will help to identify better who would benefit from this type of screening. The idea will be to use a combination of the genetic markers, family history and other important risk factors to define a woman's risk more accurate. But this will take some time before we have a system in place to do this.

missm3
Are there any patents or patent applications on these genetic markers, similarly to Myriad's BRAC1? Are these genetic markers complete gene coding DNA sequences or incomplete?

Prof Easton:
@missm3 - thanks for opportunity to clarify this. No there are no patent applications, the markers that we have published are freely available for use in genetic tests. With a few exceptions, most of the markers are not in genes and do not therefore change the actual gene sequence. They lie in non-coding regions and probably act by regulating the expression of nearby genes.

profundorosso
When are we likely to see this test available in the UK?

Prof Easton:
@profundorosso - this is very hard to say. There will be some use of risk based screening, using these genetic markers, for some women and men on a trial basis soon (in fact some studies are already underway, like the PROFILE study in prostate cancer for men with a family history, run by Ros Eeles). But widespread use of risk-based screening will take a while to implement, there are many issues to resolve - if I had to guess, at least 3 years but less than 10.

pidge1310
Who would a screening test be available for? and also would it be an economically viable use of a strained NHS budget?

Prof Easton:
@pidge1310 - indeed this all needs to be worked out with further research and this will take some time. In the short term, I think it is most likely that testing for risk using these markers will be offered to individuals who may already have an increased cancer risk, because they have a family history and are having genetic counselling.

With regard to the costs, this is clearly an important factor. However, it quite possible that including this type of risk assessment may not cost much and may even save money, because it may reduce, for example, the number of women at low risk getting mammographic screening, or the number of men at low risk getting unnecessary PSA tests or biopsies.

scubadoc
Why a "breakthrough"? Medical screening is characterised not by success, but largely by a poor understanding of sensitivity, specificity, receiver-operator curves and lead-time bias...

Prof Easton:
@scubadoc - It is true that these measures, like sensitivity and specificity, are important measures to consider in deciding whether a screening programme is worthwhile.

There has been a long debate about whether, for example, breast cancer screening by mammography is worthwhile - it detects the disease early and reduces the number of deaths from the disease, but it increases the number of women given unnecessary biopsies and treatment. What the genetic and other risk markers offer is a way of improving the equation, targeting screening on those women most likely to benefit, making the screening programme smarter.

I should also add that the gain in knowledge here is not just about identifying people at risk, it is also perhaps more importantly about understanding the biology of how cancer develops. In the long term, that may be more important.

Damien
A general question really. With all these advancements where do you expect to see Cancer Research in 20/30/40 years time? It seems we've progressed a great deal in just 10/20 years. Do you expect the rate of progress to continue, get faster, slow down?

Prof Easton:
@Damien - that is an interesting general question. I think there will be a lot of progress over the next 10-20 years. The technology for studying cancer has improved so dramatically over the last few years, in terms of being able to study the human genome, imaging, being able to study cells in far more depth than before, utilising the power of modern computing etc.etc. it hard to believe that there will not be enormous strides over the next few years.

For more questions and answers see the comment thread below. Or you can click on Prof Easton's username DougEaston to see all his comments and the comments he replied to.

Source: http://www.guardian.co.uk/science/blog/2013/mar/27/prostate-cancer-breakthrough-douglas-easton

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